Pain Relief
Methotrexаte
Methotrexаte is used to treat certain types of cancer of the breast, skin, head and neck, or lung. Methotrexаte is also used to treat severe psoriasis and rheumatoid arthritis.
Methotrexаte 2.5 mg
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Drug Uses
Methotrexаte interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.
Methotrexаte is used to treat certain types of cancer of the breast, skin, head and neck, or lung. Methotrexаte is also used to treat severe psoriasis and rheumatoid arthritis.
How to use
Use Methotrexаte as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Methotrexаte by mouth with or without food. However, you should take it the same way each time in relation to food.
Drinking extra fluids while you are taking Methotrexаte is recommended. Check with your doctor for instructions.
Be sure you understand exactly how much of Methotrexаte to take and how often you should take it. Ask your doctor or phаrmаcist if you have any questions.
It may take several weeks for your symptoms to improve. Do not stop taking Methotrexаte without checking with your doctor.
Methotrexаte works best if each dose is taken at the scheduled time.
Continue to take Methotrexаte even if you feel well. Do not miss any doses.
Drug Class and Mechanism
Methotrexаte is an antimetabolite. It works to treat cancer and psoriasis by blocking an enzyme needed for cell growth. This helps to slow the growth of cancer cells and abnormal skin cells. Exactly how Methotrexаte works to treat rheumatoid arthritis is unknown. It reduces symptoms of inflammation (e.g., pain, swelling, stiffness) caused by rheumatoid arthritis.
Missed Dose
If you miss a dose of Methotrexаte, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.
Storage
Sore Methotrexаte at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methotrexаte out of the reach of children and away from pets.
Methotrexаte interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.
Methotrexаte is used to treat certain types of cancer of the breast, skin, head and neck, or lung. Methotrexаte is also used to treat severe psoriasis and rheumatoid arthritis.
How to use
Use Methotrexаte as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Methotrexаte by mouth with or without food. However, you should take it the same way each time in relation to food.
Drinking extra fluids while you are taking Methotrexаte is recommended. Check with your doctor for instructions.
Be sure you understand exactly how much of Methotrexаte to take and how often you should take it. Ask your doctor or phаrmаcist if you have any questions.
It may take several weeks for your symptoms to improve. Do not stop taking Methotrexаte without checking with your doctor.
Methotrexаte works best if each dose is taken at the scheduled time.
Continue to take Methotrexаte even if you feel well. Do not miss any doses.
Drug Class and Mechanism
Methotrexаte is an antimetabolite. It works to treat cancer and psoriasis by blocking an enzyme needed for cell growth. This helps to slow the growth of cancer cells and abnormal skin cells. Exactly how Methotrexаte works to treat rheumatoid arthritis is unknown. It reduces symptoms of inflammation (e.g., pain, swelling, stiffness) caused by rheumatoid arthritis.
Missed Dose
If you miss a dose of Methotrexаte, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.
Storage
Sore Methotrexаte at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methotrexаte out of the reach of children and away from pets.
Warnings/Precautions
Do not use Methotrexаte if:
you are allergic to any ingredient in Methotrexаte;
you are treating psoriasis or rheumatoid arthritis and you are pregnant or breast-feeding;
you are treating psoriasis or rheumatoid arthritis and abuse alcohol or have liver problems, an immunodeficiency syndrome (e.g., AIDS), bone marrow problems, or blood problems (e.g., anemia, low white blood cell count, low platelet count);
you have moderate or severe kidney problems;
you are taking acitretin.
Contact your doctor or health care provider right away if any of these apply to you.
Important:
Methotrexаte may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Methotrexаte with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Check with your doctor before you drink alcohol while you are taking Methotrexаte.
Nausea, vomiting, and loss of appetite are common with Methotrexаte. Ask your doctor or phаrmаcist for ways to decrease these effects if they occur.
If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.
Methotrexаte may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Methotrexаte. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Methotrexаte may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Methotrexаte may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Methotrexаte. Talk with your doctor before you receive any vaccine.
Men who take Methotrexаte should always use a cоndоm when having sex with a woman who may become pregnant. Do this for as long as you take Methotrexаte and for 3 months after you stop taking it.
Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Lab tests, including albumin levels, complete blood counts, and liver, lung, and kidney function, may be performed while you use Methotrexаte. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Methotrexаte with caution in the elderly; they may be more sensitive to its effects.
Methotrexаte should be used with extreme caution in children younger than 2 years old; safety and effectiveness in these children have not been confirmed.
Pregnancy and breast-feeding: Methotrexаte may cause birth defects and fetal and newborn death if you take it while you are pregnant. Do not become pregnant while you are using it. Use an effective form of birth control while you take Methotrexаte and for at least 1 ovulatory cycle after you stop taking it. If you think you may be pregnant, contact your doctor right away. Methotrexаte is found in breast milk. Do not breast-feed while taking Methotrexаte.
Do not use Methotrexаte if:
you are allergic to any ingredient in Methotrexаte;
you are treating psoriasis or rheumatoid arthritis and you are pregnant or breast-feeding;
you are treating psoriasis or rheumatoid arthritis and abuse alcohol or have liver problems, an immunodeficiency syndrome (e.g., AIDS), bone marrow problems, or blood problems (e.g., anemia, low white blood cell count, low platelet count);
you have moderate or severe kidney problems;
you are taking acitretin.
Contact your doctor or health care provider right away if any of these apply to you.
Important:
Methotrexаte may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Methotrexаte with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Check with your doctor before you drink alcohol while you are taking Methotrexаte.
Nausea, vomiting, and loss of appetite are common with Methotrexаte. Ask your doctor or phаrmаcist for ways to decrease these effects if they occur.
If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.
Methotrexаte may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Methotrexаte. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Methotrexаte may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Methotrexаte may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Methotrexаte. Talk with your doctor before you receive any vaccine.
Men who take Methotrexаte should always use a cоndоm when having sex with a woman who may become pregnant. Do this for as long as you take Methotrexаte and for 3 months after you stop taking it.
Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Lab tests, including albumin levels, complete blood counts, and liver, lung, and kidney function, may be performed while you use Methotrexаte. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Methotrexаte with caution in the elderly; they may be more sensitive to its effects.
Methotrexаte should be used with extreme caution in children younger than 2 years old; safety and effectiveness in these children have not been confirmed.
Pregnancy and breast-feeding: Methotrexаte may cause birth defects and fetal and newborn death if you take it while you are pregnant. Do not become pregnant while you are using it. Use an effective form of birth control while you take Methotrexаte and for at least 1 ovulatory cycle after you stop taking it. If you think you may be pregnant, contact your doctor right away. Methotrexаte is found in breast milk. Do not breast-feed while taking Methotrexаte.
Possible Side Effects
Check with your doctor if any of these most common side effects persist or become bothersome:
dizziness; headache; loss of appetite; mild hair loss; nausea; stomach pain or upset; tiredness; vomiting.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the urine; calf or leg pain or swelling; change in the amount of urine; chest pain; coma; confusion; coughing up blood; dark urine; diarrhea; difficult or painful urination; dry cough; fever, chills, or sore throat; menstrual changes; mental or mood changes; mouth sores; one-sided weakness; red, swollen, peeling, or blistered skin; seizures; severe or persistent nausea or vomiting; shortness of breath; speech changes; unusual bleeding or bruising; unusual pain and discoloration of the skin; unusual tiredness or weakness; vision changes or vision loss; yellowing of skin or eyes.
More Information
Methotrexаte is to be used only by the patient for whom it is prescribed. Do not share it with other people.
Check with your doctor if any of these most common side effects persist or become bothersome:
dizziness; headache; loss of appetite; mild hair loss; nausea; stomach pain or upset; tiredness; vomiting.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the urine; calf or leg pain or swelling; change in the amount of urine; chest pain; coma; confusion; coughing up blood; dark urine; diarrhea; difficult or painful urination; dry cough; fever, chills, or sore throat; menstrual changes; mental or mood changes; mouth sores; one-sided weakness; red, swollen, peeling, or blistered skin; seizures; severe or persistent nausea or vomiting; shortness of breath; speech changes; unusual bleeding or bruising; unusual pain and discoloration of the skin; unusual tiredness or weakness; vision changes or vision loss; yellowing of skin or eyes.
More Information
Methotrexаte is to be used only by the patient for whom it is prescribed. Do not share it with other people.
